UREA (Intra-amniotic)?
Some commonly used brand names are:
In the U.S.?
Another commonly used name is carbamide.
? Not commercially available in Canada.
Category
Description
Intra-amniotic urea (yoor-EE-a) is given by injection into the uterus to causeabortion. It is to be administered only by or under the immediate care ofyour doctor. It is available in the following dosage form:
Parenteral- Injection (U.S.)
Before Receiving This Medicine
In deciding to use a medicine, the risks of taking the medicine must beweighed against the good it will do. This is a decision you and your doctorwill make. For urea, the following should be considered:
Allergies?Tell your doctor if you have ever had any unusual orallergic reaction to urea. Also tell your health care professional if youare allergic to any other substances, such as foods, preservatives, or dyes.
Children?Although there is no specific information comparing use of ureain teenagers with use in other age groups, this medicine is not expected tocause different side effects or problems in teenagers than it does in adults.
Other medicines?Although certain medicines shouldnot be used together at all, in other cases two different medicines may beused together even if an interaction might occur. In these cases, your doctormay want to change the dose, or other precautions may be necessary. Tell yourhealth care professional if you are taking any other prescription or nonprescription(over-the-counter [OTC]) medicine.
Other medical problems?The presence of other medicalproblems may affect the use of urea. Make sure you tell your doctor if youhave any other medical problems, especially:
- Diabetes mellitus (sugar diabetes)
- Fibroid tumors of the uterus
Proper Use of This Medicine
During theabortion procedure, you should drink fluids to help prevent your body fromlosing too much water.
Dosing?The dose of urea will be different for differentpatients. Follow your doctor's orders. The dosewill be given by your doctor in a health care setting, such as a hospitalor clinic. The following information includes only the average doses of urea.
- For injection dosage form:
- For causing abortion:
- Adults and teenagers?Up to 250 milliliters (mL) injected throughthe abdomen into the uterus after the same amount of fluid is taken out ofthe bag around the fetus (amniotic sac). The injection may be repeated 48hours after the first dose if needed.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwantedeffects. Although not all of these side effects may occur, if they do occurthey may need medical attention.
Check with your healthcare professional immediately if either of the following side effectsoccurs during the time that the injection is being given:
Check with your health careprofessional as soon as possible if any of the following side effects occur:
Rare
Confusion; irregular heartbeat; muscle cramps or pain; numbness, tingling,pain, or weakness in hands or feet; unusual tirednessor weakness; weakness and heaviness of legs
Other side effects may occur that usually do not need medical attention.However, check with your health care professional if any of the followingside effects continue or are bothersome:
After the procedure is completed,this procedure may still produce some side effects that need medical attention.Check with your doctor if you notice any of the following side effects:
Chills or shivering; fever; foul-smelling vaginal discharge; increasein bleeding of the uterus; pain in lower abdomen
Other side effects not listed above mayalso occur in some patients. If you notice any other effects, check with yourhealth care professional.
Revised: 02/22/2000
