Tropical sprue
Definition
Tropical sprue is a malabsorption syndrome of unknown cause that is common in the tropics and subtropics.
Causes
The cause of this disease is unknown, but it may be related to an infectious organism. The condition affects residents of or visitors to the tropics. The main symptom is diarrhea, which may get better after leaving tropical areas, but may reappear years later. Risk factors are living in the tropics or long travel to tropical destinations.
Symptoms
In children, sprue most often presents with growth failure and delayed skeletal maturation.
Exams and Tests
Treatment
Treatment begins with rehydration with fluids and electrolytes. Replacement of folate, iron, vitamin B12, and other nutrients may also be needed. Antibiotic therapy with tetracycline is given at the beginning of treatment.
Oral tetracycline is usually not prescribed for children until after all permanent teeth have erupted. It can permanently discolor teeth that are still forming.
Outlook (Prognosis)
The outcome is expected to be good with treatment.
Possible Complications
Vitamin and mineral deficiencies are common complications.
When to Contact a Medical Professional
Call your provider if you experience prolonged diarrhea or other symptoms of this disorder, especially after spending time in the tropics.
Call your provider if tropical sprue symptoms worsen or do not improve with treatment, or if new symptoms develop.
Prevention
Other than avoiding living in or traveling to tropical climates, there is no known prevention for tropical sprue.
Review Date:
5/4/2006
Reviewed By:
Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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